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A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes
《医学前沿(英文)》 2023年 第17卷 第3期 页码 458-475 doi: 10.1007/s11684-022-0968-4
关键词: LU domain-containing protein family novel human gene LY6A pituitary tumor biomarker nonsynonymous SNP GPI-anchored protein
《医学前沿(英文)》 2023年 第17卷 第4期 页码 714-728 doi: 10.1007/s11684-022-0959-5
关键词: FRMD6 lung cancer mTOR pathway
Dual faces of SH2-containing protein-tyrosine phosphatase
null
《医学前沿(英文)》 2012年 第6卷 第3期 页码 275-279 doi: 10.1007/s11684-012-0216-4
PTPN11, which encodes tyrosine phosphatase Shp2, is a critical gene mediating cellular responses to hormones and cytokines. Against original prediction as tumor suppressor for tyrosine phosphatases, PTPN11 was first identified as a proto-oncogene because activating mutations of this gene are associated with leukemogenesis. However, most recent experimental data suggest PTPN11/Shp2 acting as a tumor suppressor in hepatocarcinogenesis. This review focuses on the tumor-promoting or suppressing roles of the gene PTPN11/Shp2 in different cell types.
Keratin 5-Cre-driven deletion of
Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue
《医学前沿(英文)》 2020年 第14卷 第3期 页码 305-317 doi: 10.1007/s11684-019-0722-8
关键词: acne inversa mouse model interleukin 1 family member 6 small proline rich protein 2D key inflammatory cytokine
PROTECTIVE ROLES OF D1 PROTEIN TURNOVER AND THE XANTHOPHYLL CYCLE IN TOMATO (
Tao LU, Jiazhi LU, Mingfang QI, Zhouping SUN, Yufeng LIU, Tianlai LI
《农业科学与工程前沿(英文)》 页码 262-279 doi: 10.15302/J-FASE-2021383
关键词: D1 turnover photoinhibition photoprotection photosynthesis tomato xanthophyll cycle
Numerical study on natural convection in a square enclosure containing a rectangular heated cylinder
Jianhua LU, Zhaoli GUO, Zhenhua CHAI, Baochang SHI,
《能源前沿(英文)》 2009年 第3卷 第4期 页码 373-380 doi: 10.1007/s11708-009-0078-x
关键词: natural convection buoyant regime heated cylinder lattice Boltzmann
Zhen Li, Zhaofu Qiu, Ji Yang, Benteng Ma, Shuguang Lu, Chuanhui Qin
《环境科学与工程前沿(英文)》 2018年 第12卷 第6期 doi: 10.1007/s11783-018-1082-3
Spent FCC catalyst with lanthanum is proposed as a novel P-removal adsorbent. The spent FCC catalyst exhibits 99% adsorption efficiency for low P-concentration wastewater (C0 <5.0 mg/L). High affinity, endothermic reaction and fast sorption kinetics are achieved. The phosphate is adsorbed in the form of LaPO4 and KH2PO4.
关键词: Spent FCC catalyst Phosphate removal Adsorption Lanthanum
Junguo HE, Guangming ZHANG, Haifeng LU,
《环境科学与工程前沿(英文)》 2010年 第4卷 第3期 页码 334-339 doi: 10.1007/s11783-010-0239-5
关键词: purple nonsulfur bacteria (PNSB) Rhodobacter sphaeroides Z08 soybean wastewater cost effective
Development and clinical trial of a novel bioactive bone cement
LEONG John, LI Zhaoyang, LU William
《医学前沿(英文)》 2008年 第2卷 第2期 页码 117-126 doi: 10.1007/s11684-008-0022-1
关键词: bioactivity effectiveness strontium-containing hydroxyapatite osseointegration sufficient mechanical
Moving target detection in the cepstrum domain for passive coherent location (PCL) radar
Ji-chuan LI,Xiao-de LU,Hui ZHANG,Peng-cheng YANG,Yu LIU,Mao-sheng XIANG
《信息与电子工程前沿(英文)》 2015年 第16卷 第9期 页码 785-795 doi: 10.1631/FITEE.1500036
关键词: Moving target detection Cepstrum techniques Cross ambiguity function (CAF) Passive coherent location (PCL) radar
Epidemiological study of a von Hippel-Lindau family in northwest China
null
《医学前沿(英文)》 2013年 第7卷 第3期 页码 378-385 doi: 10.1007/s11684-013-0276-0
von Hippel-Lindau (VHL) disease is a rare, inherited neoplastic disease characterized by hemangioblastomas (HBL) of the central nervous system (CNS), retinal angiomas, renal cell carcinomas (RCC), pancreatic endocrine tumors (PETs), pheochromocytomas, paragangliomas, and visceral cysts. We encountered a large VHL family in northwest China and conducted a systematic screening of the family members based on their epidemiological and clinical characteristics. A self-designed questionnaire was used to collect the general sociodemographic and health information of the family members. For the preliminary family screening, physical examination and abdomen B ultrasonography were performed. The suspected patients were subjected to cranial computerized tomography and fundus examination. The clinical data of the patients with confirmed VHL disease were collected from hospital records. A total of 63 lineal descendants in six generations were observed in the family (generations O, A, B, C, D, E), including 9 dead suspected cases (6 males, 3 females) and 10 living cases (2 males, 8 females). Among the 10 living cases, 4, 2, 1, 3, 4, 8, and 2 manifested HBLs of the CNS, PETs, RCC, pancreatic cysts, renal cysts, pheochromocytomas (4 hemi and 4 bilateral), and paragangliomas, respectively. Data showed that the morbidity of VHL disease in generation C was lower than that in generation B, but the age of onset was younger. This study is the first to report VHL disease in northwest China and VHL-associated PET cases in Chinese. Therefore, follow-up checkups of the family should be focused on younger generations. Proper family screening protocols should be followed for the treatment of patients with VHL disease.
关键词: von Hippel-Lindau disease epidemiology family screening pancreatic endocrine tumor
Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cell
Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 106-111 doi: 10.1007/s11684-010-0004-y
关键词: hepatitis B virus X gene glomerular mesangial cell line extracellular regulated protein kinases tumor necrosis factor-α
朵英贤
《中国工程科学》 1999年 第1卷 第2期 页码 57-61
主要叙述我国轻武器行业两代工程技术人员在基础很薄弱的情况下,团结合作,用科学和严密的方法,在很短的时间内研制出高水平的步兵班用枪族,使中国步兵枪械达到世界先进水平,受到军方高度评价。该枪族已于1997年元月正式装备驻港部队,并将陆续装备全军。
Time-domain and frequency-domain approaches to identification of bridge flutter derivatives
Zhengqing CHEN
《结构与土木工程前沿(英文)》 2009年 第3卷 第2期 页码 173-179 doi: 10.1007/s11709-009-0034-1
关键词: long-span bridges wind-induced vibration flutter derivatives forced vibration test time-domain method frequency-domain method
《医学前沿(英文)》 页码 1006-1009 doi: 10.1007/s11684-023-1000-3
关键词: family craniofacial microsomia Identification novel mutations
标题 作者 时间 类型 操作
A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes
期刊论文
FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression
期刊论文
Keratin 5-Cre-driven deletion of
Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue
期刊论文
PROTECTIVE ROLES OF D1 PROTEIN TURNOVER AND THE XANTHOPHYLL CYCLE IN TOMATO (
Tao LU, Jiazhi LU, Mingfang QI, Zhouping SUN, Yufeng LIU, Tianlai LI
期刊论文
Numerical study on natural convection in a square enclosure containing a rectangular heated cylinder
Jianhua LU, Zhaoli GUO, Zhenhua CHAI, Baochang SHI,
期刊论文
Investigation of phosphate adsorption from an aqueous solution using spent fluid catalytic cracking catalyst containing
Zhen Li, Zhaofu Qiu, Ji Yang, Benteng Ma, Shuguang Lu, Chuanhui Qin
期刊论文
Treatment of soybean wastewater by a wild strain Rhodobacter sphaeroides and to produce protein under
Junguo HE, Guangming ZHANG, Haifeng LU,
期刊论文
Development and clinical trial of a novel bioactive bone cement
LEONG John, LI Zhaoyang, LU William
期刊论文
Moving target detection in the cepstrum domain for passive coherent location (PCL) radar
Ji-chuan LI,Xiao-de LU,Hui ZHANG,Peng-cheng YANG,Yu LIU,Mao-sheng XIANG
期刊论文
Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cell
Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,
期刊论文
Time-domain and frequency-domain approaches to identification of bridge flutter derivatives
Zhengqing CHEN
期刊论文